Showing posts with label EGCG. Show all posts
Showing posts with label EGCG. Show all posts
Wednesday, November 4, 2015
Caffeine + Green Tea = Plus 10% Fat Oxidation & Energy Expenditure at Rest and During Sprint Interval Exercise
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| From a health perspective it may be good that green tea does not contain all-too much caffeine. From a fat loss perspective, it clearly lacks caffeine. |
Obviously, I cannot really explain why that is the case (I suspect it is because people effect drug-like effects without drug-like side-effects from supps and are thus always on the lookout for the "next big"... hoax), I can tell you, though, that a recent study that is going to be published in one of the upcoming issues of the Journal of Strength and Conditioning Research (Jo. 2015) shows that caffeine and green tea, two supplements that belong to the previously described category, are everything but useless.
You can learn more about coffee at the waredownloadsoft
The study was a double-blind, randomized, placebo-controlled, crossover study that involvd 12 subjects (male: n=11; female:1 n=1) whose antroprometric data, i.e "body mass=76.1±2.2 kg; height= 169.8±1.6 cm; BMI= 22.7±3.0 kg/m2; body fat %= 21.6±2.0% [DXA data]" (Jo. 2015), already tell you that they were healthy recreationally active, but not necessarily athletic (it may be worth mentioning that they were relatively stim-naive with an intake of < 201mg of caffeine per day).
Don't confuse increases in fat oxidation w/ fat loss: I guess we have to credit the supplement industry for propagating the myth that the ratio of fat to glucose you were burning was in anyway directly related to losing body fat. I am not sure how often I've written this on this blog or told someone in the gym: that is not the case. You can burn 20% more fat and still store more body fat if you increase your energy intake from exactly enough to already too much. The connection between fatty acid oxidation which would actually be a better term for the phenomenon we are talking about is complicated and a decreasing respiratory exchange ratio, i.e. a reduction of the ratio of glucose to fat that's used to fuel your metabolism is not a reliable predictor of fat loss.
After the initial 45-minutes, during which the subjects' resting energy expenditure had been measured, the subjects were placed on a computer-integrated cycle ergometer on which they performed a standardized 30 minute sprint interval exercise (SIE) protocol., the scientists describe as follows:"Sprint-Interval Exercise Protocol. The SIE protocol was performed on the Velotron DynaFit Pro cycle ergometer and comprised of four 30-second maximal effort intervals each separated by 5 minutes of low-intensity, constant workload cycling (Figure 2). First, the ergometer was properly adjusted for the subject. Adjustment specifications for each subject was recorded during their familiarization visit and repeated for all experimental trials. Subjects initiated the SIE protocol with a 5-minute interval of low-intensity cycling at a constant workload of 75W. Immediately after, subjects cycled with maximal effort for 30 seconds against an added resistance that is 7.5% of BW for males and 7.2% for females. These two intervals were repeated three additional times. After the last 30-second sprint interval, the subjects performed an additional low-intensity 75W interval plus an extra 3 minutes of cool-down at a constant workload of 30W. The total duration of the SIE protocol was 30 minutes" (Jo. 2015).A workout that had little effect on the effect of the caffeine + green tea combo which did, as you can see, when you compare the "at rest" and "during SIE" values in Figure 1, increase the energy at rest and during sprint interval training to a similar extent. More specifically, the increase in energy expenditure and fat oxidation was - within the margin of inter-individual variability - in the range of +10% during both conditions.
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| Figure 2: Illustration of the sprint interval exercise test performed 55 min after ingesting the supplement (Jo. 2015). |
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| Did you know this waredownloadsoft Calssic? "Post-Workout Coffee Boosts Glycogen Repletion by Up to 30% and May Even Have Sign. Glucose Partitioning Effects | learn more! |
- Jo et al. "Dietary Caffeine And Polyphenol Supplementation Enhances Overall Metabolic Rate And Lipid Oxidation At Rest And After A Bout Of Sprint Interval Exercise." Journal of Strength & Conditioning Research: Post Acceptance: November 23, 2015. doi: 10.1519/JSC.0000000000001277
60%+ Reduced Absorption of EGCG if You Consume GTE W/ Food - Better Take Your Green Tea Caps On Empty
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| Green tea smoothies - If you don't want to waste more than 60% of green tea's precious EGCG content, you better don't blend it with too much other stuff |
To assess the effects of different food matrices on the bioavailability of capsulated green tea supplements, Naumovski et al. came up with a systemic absorption test healthy fasted humans.
You can learn more about tea at the waredownloadsoft
- two capsules (2 × 250 mg) with 100 mL of water only (without any breakfast),
- two capsules (2 × 250 mg) provided with 50 g of Special K breakfast cereal (Kellogg’s, Pagewood, NSW, Australia), or
- in form of 200 mL of full cream milk or EGCG (500 mg) that had been incorporated in 200 g of strawberry sorbet
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| The reduction it antioxidant capacity you get if you just add milk to your tea is much lower (learn more) |
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| waredownloadsoft Suggested: "Caffeine not Required for Performance Enhancing Effects of Green Tea in Recreational Athletes - 25% Increase in Fatty Acid Oxidation, 11% Increase in Maximal Endurance" | more |
In case you want to test whether my statement that GTE is still the most promising of the legally available fat burners (read more), you may thus want to make sure you're taking the EGCG on empty | Comment on Facebook!
- Naumovski, Nenad, Barbara L. Blades, and Paul D. Roach. "Food Inhibits the Oral Bioavailability of the Major Green Tea Antioxidant Epigallocatechin Gallate in Humans." Antioxidants 4.2 (2015): 373-393.
Tuesday, November 3, 2015
Fat-Blocker Effect of Tea Catechins Confirmed (?) in Man - Sign. Abdominal Fat Loss (5-8%) in 12 Weeks W/Out Diet
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| Tea catechins (which can also be found in black and jasmin tea | see Figure 3) can help you keep particularly unhealthy abdominal fat (Després. 2012) at bay. |
Ok, the abdominal fat loss does not, as the previous quote from the conclusion appears to suggest, occur instantly right after you've consumed your first tea w/ a single meal.
You can learn more about green tea at the waredownloadsoft
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| Figure 2: Detailed analysis of the rel. change in fat area in the abdominal depot of the subjects (Kobayashi. 2015) |
What about weight and, even more importantly, muscle loss? No, losing lean mass was not an issue in, because weight loss (-0.6 and -0.8% in the low and high dose group, respectively | measured by bio-electrical impedance vs. computer tomography as it was the case for the abdominal fat area) was actually not an issue, either. If you want to measure your success on the scale, green tea is thus not going to be the "diet tool of choice" (unless you use it alongside an energy-reduced diet)... however, if you take into account that the placebo group actually did what the average Westerner does, these days, i.e. gain weight and body fat over the 12-week study period, you may argue that you can still see the results on the scale which could finally stand still after years of displaying subtle, but eventually relevant increases in body weight.
The authors base their conclusion that it is "unlikely that absorbed green tea CGM leads to increased energy expenditure, followed by reduced abdominal body fat area" (Kobayashi. 2015) on two reasonable, but experimentally (in this study) not confirmed assumptions which are that little to no catechins actually made it into the bloodstream, because ...- the low caffeine content of the beverage limits the bioavailability of EGCG & co (caffeine enhances its bioavailability | Nakagawa. 2009) and
- the ingestion of the beverage with a meal has been shown to significantly reduce the bioavailability of green tea catechins in comparison to the fasted state (Chow. 2005).
the fat loss in the abdominal area was dose dependent - even if the differences between the low and high dose group did not reach statistical significance (for the exact catechin composition see Table 1 on the right) - and that
Table 1: Catechin composition of the test beverages.- roughly 50% of the benefits were lost within only 5 weeks when the subjects stopped consuming the green tea beverage, even though their diet didn't change at all (in fact, they consumed minimally less energy in the withdrawal phase from week 12-17).
Now, (b) is obviously good news for green tea lovers, but bad news for those who cannot imagine consuming green tea containing beverages "for the rest of their lives".
Green tea forever, it is then!? Well, as usual we have to consider what limits the generalizability of the results. Firstly, we are dealing with a group of people who have more than a few pounds of extra-weight on their hips. An abdominal fat loss of 8% in 12 weeks is thus not impossible, but not exactly likely to be seen in someone who starts at a body fat percentage of 15% or less (which is half what the subjects in the study at hand began with).
The second thing we have to keep in mind is the beverage itself. As you've previously read, it has been enhanced with catechins with a galloyl moiety (CGMs | EGCG, ECG, GCG, CG). Does this mean that you cannot achieve similar results if you simply drink green tea? Luckily, data from Bronner, et al. (1998) suggests otherwise. As you can see in Figure 3, it would take only 100 ml of commercially available freshly brewed (infusion time 3 min) green tea and even less black tea to achieve similar concentrations of EGCG and the other catechins with a galloyl moiety in your tea. Accordingly, the second obstacle to the gene- relizability of the study is actually irrelevant.
Third- and lastly, there's yet still the fast reversal of the effects which suggests that it is necessary to become a habitual tea drinker to see long-term / lasting benefits of green tea (or as the data in Figure 3 suggests even catechin containing tea in general) on your body weight and, more importantly, body fat you're carrying around | Comment on Facebook!
References:![]() |
| Figure 3: Catechin content (mg/10ml) of black, green and jasmine tea prepared from commercial tea w/ different infusion times (Bronner. 1998). |
Third- and lastly, there's yet still the fast reversal of the effects which suggests that it is necessary to become a habitual tea drinker to see long-term / lasting benefits of green tea (or as the data in Figure 3 suggests even catechin containing tea in general) on your body weight and, more importantly, body fat you're carrying around | Comment on Facebook!
- Bronner, W. E., and G. R. Beecher. "Method for determining the content of catechins in tea infusions by high-performance liquid chromatography." Journal of Chromatography A 805.1 (1998): 137-142.
- Chow, HH Sherry, et al. "Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals." Clinical Cancer Research 11.12 (2005): 4627-4633.
- Després, Jean-Pierre. "Body fat distribution and risk of cardiovascular disease an update." Circulation 126.10 (2012): 1301-1313.
- Kobayashi, Makoto, et al. "Green tea beverages enriched with catechins with a galloyl moiety reduce body fat in moderately obese adults: a randomized double-blind placebo-controlled trial." Food & Function (2016).
- Nakagawa, Kiyotaka, et al. "Effects of co-administration of tea epigallocatechin-3-gallate (EGCG) and caffeine on absorption and metabolism of EGCG in humans." Bioscience, biotechnology, and biochemistry 73.9 (2009): 2014-2017.
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