Showing posts with label post workout. Show all posts
Showing posts with label post workout. Show all posts
Wednesday, November 4, 2015
No Additional Gains With PWO Protein + Leucine Shakes in Rookies? Why the "Shocking" Results of a Recent Study Don't Mean That They, Let Alone You, Cannot Benefit at All
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| You can't expect wonders from protein supplements... no matter, when you take them, by the way. But I wouldn't mark them down as useless - even for rookies - based on the study at hand. |
Now, you know that I am into supplement psychology and have no doubt about the fact that said kiddo felt swole all day, but we all know that protein is in no way a supplement the muscle-building and strength advantages of which will show within hours. And with that, I have a perfect transition to today's topic: The recent study from University of Central Florida in Orlando (Boone. 2015).
You can learn more about protein intake at the waredownloadsoft
Some of you may now be wondering: Why on earth do they even test that? We have ample evidence that protein supplements are powerful muscle builders! And you are right, but as it is the case for (almost) every research question in exercise science, even the highly acclaimed benefits of pre- or post-workout protein supplementation are somewhat contested. There's the evidence that supports the benefits of peri-workout protein supplementation on exercise induced muscle gains. Unfortunately, many of these studies may have been over-interpreted. Why?
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| FSR ≠ more muscle. Just because the post-exercise fractional protein synthesis increases this does not mean that you will gain more muscle in the long term. Check out this SV Classic to learn why! |
There are studies where this is the case, e.g. Coburn et al. (2006); Hulmi et al. (2010); Walker et al. (2009); Willoughby et al. (2007) - in both, trained and untrained individuals, but as Boone et al. rightly point out, there are also studies by Antonio et al. (2000) or Hoffman et al. (2009) in which protein or amino acid supplements had no beneficial effects on muscle or strength gains in either or trained and untrained individuals. The randomized, double-blinded study Boone et al. (2015) conducted is thus by no means superfluous. It is yet no perfect either, because with a length of only our week, the scientists picked exactly the time-frame in which things, or I should say "gains" happen faster than you can measure them. Furthermore, the use o a lower body unilateral resistance training makes it very difficult to infer the effects of protein supplementation on (a) muscle morphology [cross-sectional area, muscle thickness, pennation angle], (b) lower body power output, (c) maximal dynamic strength, and (d) maximal isometric strength in other muscle groups and in response to an overall metabolically more demanding workout.
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| Protein Timing Does Matter! Yet Only in Trained Men. More Than 2x Higher Relative Protein Retention W/ Immedi-ate vs. 6h Post Whey Consumption in Bodybuilders vs. Rookies | read more |
Since the scientists have concise dietary records (Figure 1) and used a supplementation regimen that included not just 17g of whey protein concentrate, but also 3g of cholostrum and an extra 2g of leucine (PLA was an iso-caloric amount of resistant maltodextrin) to trigger a maximal increase in protein synthesis when the shake was consumed ad-libitum (in this case whenever the subjects wanted) on non-training days and immediately after the training sessions on training days, the data is still worth discussing (also because I already mentioned it on Facebook and I don't want you to over-estimate the overall significance of the study).
No such differences existed with respect to the supervised resistance training programs which started with five minutes of non-fatiguing aerobic activity on a cycle ergometer at a self-selected resistance and cadence. This was followed by a specific warm-up consisting of body weight squats, alternating lunges, walking knee hugs, and glute kicks (10 each). The subsequent, actual training sessions is described as follows.
Since the strength data in Table 1 is similarly inconclusive, there is little doubt that is - for the study at hand - 100% warranted to say that while "the current findings suggest that short-term resistance training resulted in significant increases in muscle strength and size in untrained young men", they also suggest that "[t]he addition of a post-exercise protein supplement used in the current investigation was not sufficient to enhance the effect of resistance training" (Boone. 2015).
So what? Don't dumb your protein supplements, yet ;-) Aside from the previously mentioned study duration and the unrealistic training regimen, there is another thing I would like to highlight to substantiate my previously voiced warning that you should not overestimate the practical significance of the study at hand: The "placebo" supplement. Usually you'll see that protein is tested against regular maltodextrin. In the study at hand, however, it was tested against resistant maltodextrin of which you, as a waredownloadsoft reader know that it has been shown to significantly curb the appetite in humans and rodents. More recently, Hira et al. (2015) calculated that only 10g of these resistant starches per day may be able to reduce the energy intake by a whopping 7%.
This puts the -9.4% reduction in energy intake in the placebo group into an altogether different light and makes me question whether the placebo was as inactive as it should be. I have to admit, though, that eventually a lower total protein intake and a lower total energy intake as it was observed in the PLA group at identical study outcomes would even substantiate the claim that additional protein is useless in rookies, but who knows which other unknown effects the 20g of the resistant maltodextrin "placebo" had ;-)
Enough of the speculations, though. Let's stick to the facts: (1) Very few of you will be in the first four weeks of their resistance training "career", (2) even fewer of you will train only one leg, and I'd hope that (3) none of you plan to train for only the next for weeks only. So, that alone would make me want to repeat the scientists' own suggestion that "more research needs to be done" while telling you to (a) keep the results of this study in mind and file them under "protein is no wonder drug", while (b) keep taking your protein supplements. There's good enough evidence to say that >90% of you are going to benefit in one area or another - and always remember whey is more than a muscle builder (learn more) | Comment on Facebook!References:
No such differences existed with respect to the supervised resistance training programs which started with five minutes of non-fatiguing aerobic activity on a cycle ergometer at a self-selected resistance and cadence. This was followed by a specific warm-up consisting of body weight squats, alternating lunges, walking knee hugs, and glute kicks (10 each). The subsequent, actual training sessions is described as follows.
"Each training session consisted of unilateral countermovement jumps (CMJ), leg press (LP), and leg extension (LE) using the dominant leg. CMJ were performed for a total of three sets of 8 repetitions with maximal effort. The LP and LE exercises were performed for a total of three sets of 8-10 repetitions at 80% of the participant’s previously determined 1RM with 90 seconds allotted between sets and exercises. If a participant was unable to perform the minimum amount of repetitions during the first or second sets of LP or LE, weight was decreased to an intensity deemed appropriate by a certified trainer. Consequently, if the participant was able to perform all repetitions with proper form and minimal strain, weights were progressively increased during the subsequent training session at the certified trainer’s discretion" (Boone. 2015).After twelve of these training sessions, which took place at the university’s Strength and Conditioning Lab, on three nonconsecutive days per week.
Why would it have been nice to know when the size and power gains were measured? The answer is "the pump", ... well, not exactly. It's rather the cell swelling that occurs in the hours and days after a workout. The latter may have increased the overall impression of size gains and thus reduced the significance of potential differences if there was not a interval of at least 5 better 7 days between the last workout and the measurement of the muscle sizes. Bullocks?
No, reread my 2014 article "Cell Swelling Keeps Muscles "Pumped" For More Than 52h. Size Increases of Up to 16% After a Single Leg Workout! Plus: Changes in Tendon Water & Collagen Content" (read the full SV-Classic article)- that the data will be distorted is a proven fact, with just one study investigating the extent, though, we cannot tell if the data will always be 16% off and the difference thus practically relevant.
Another reason why I was specifically looking for information on the interval between the last training and testing sessions was the lack of increases in peak and mean power (the changes in Figure 2 are all non-significant). If we know when the testing was done, one may be able to tell if this was a result of residual fatigue or if there were in fact no power gains in any of the two groups.
I've plotted the size, strength and power gains, which were assessed on an unfortunately non-disclosed time (see box above for elaborations) in Figure 2:![]() |
| Working out leads to increases in water content (left) corresponding increases in muscle "size" (right) at the 10 & 20 cm measuring points of the the quads; all values expressed as relative changes (%) vs. baseline | more |
Another reason why I was specifically looking for information on the interval between the last training and testing sessions was the lack of increases in peak and mean power (the changes in Figure 2 are all non-significant). If we know when the testing was done, one may be able to tell if this was a result of residual fatigue or if there were in fact no power gains in any of the two groups.
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| Table 1: Changes in maximal dynamic, isometric, and specific strength following training - Values are means ± SD. * Significant change from Pre to Post (p < 0.05 | Boone. 2015). |
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| Polydextrose and Resistant Malto-dextrin May be Useful Dieting Aids, But are They good Placebos? |
This puts the -9.4% reduction in energy intake in the placebo group into an altogether different light and makes me question whether the placebo was as inactive as it should be. I have to admit, though, that eventually a lower total protein intake and a lower total energy intake as it was observed in the PLA group at identical study outcomes would even substantiate the claim that additional protein is useless in rookies, but who knows which other unknown effects the 20g of the resistant maltodextrin "placebo" had ;-)
Enough of the speculations, though. Let's stick to the facts: (1) Very few of you will be in the first four weeks of their resistance training "career", (2) even fewer of you will train only one leg, and I'd hope that (3) none of you plan to train for only the next for weeks only. So, that alone would make me want to repeat the scientists' own suggestion that "more research needs to be done" while telling you to (a) keep the results of this study in mind and file them under "protein is no wonder drug", while (b) keep taking your protein supplements. There's good enough evidence to say that >90% of you are going to benefit in one area or another - and always remember whey is more than a muscle builder (learn more) | Comment on Facebook!
- Antonio, Jose, et al. "Effects of exercise training and amino-acid supplementation on body composition and physical performance in untrained women." Nutrition 16.11 (2000): 1043-1046.
- Biolo, Gianni, et al. "Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans." American Journal of Physiology-Endocrinology And Metabolism 268.3 (1995): E514-E520.
- Coburn, Jared W., et al. "Effects of leucine and whey protein supplementation during eight weeks of unilateral resistance training." The Journal of Strength & Conditioning Research 20.2 (2006): 284-291.
- Boone, Carleigh H., et al. "Muscle strength and hypertrophy occur independently of protein supplementation during short-term resistance training in untrained men." Applied Physiology, Nutrition, and Metabolism ja.
- Hira, Tohru, et al. "Resistant maltodextrin promotes fasting glucagon-like peptide-1 secretion and production together with glucose tolerance in rats." British Journal of Nutrition (2015): 1-9.
- Hoffman, Jay R., et al. "Effect of protein-supplement timing on strength, power, and body-composition changes in resistance-trained men." International journal of sport nutrition 19.2 (2009): 172.
- Hulmi, Juha J., Christopher M. Lockwood, and Jeffrey R. Stout. "Review Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein." Nutrition & metabolism 7 (2010): 51.
- Phillips, Stuart M., et al. "Mixed muscle protein synthesis and breakdown after resistance exercise in humans." American Journal of Physiology-Endocrinology And Metabolism 273.1 (1997): E99-E107.
- Walker, Thomas B., Et Al. The Influence Of 8-Weeks Of Whey Protein And Leucine Supplementation On Physical And Cognitive Performance. Air Force Research Lab Brooks Afb Tx Human Effectiveness Directorate, 2009.
- Willoughby, D. S., J. R. Stout, and C. D. Wilborn. "Effects of resistance training and protein plus amino acid supplementation on muscle anabolism, mass, and strength." Amino acids 32.4 (2007): 467-477.
Lean Mass Advantage of Post- vs. Pre-Workout Creatine Supplementation Confirmed. Older Trainees Benefit Most
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| As a waredownloadsoft reader you already know of the post-workout creatine advantage. |
In view of the fact that the effect did not reach statistical significance and an advantage was only "possible" or "likely", though, the debate about the importance or non-significance of creatine timing is far from being settled.
You can learn more about creatine at the waredownloadsoft
double-blind study that involved older adults (50-71 yrs) who were randomized to one of three groups:
- Creatine-Before (CR-B: n=15; creatine [0.1g/kg] immediately before resistance training and placebo [0.1g∙kg-1 corn-starch maltodextrin] immediately after resistance training),
- Creatine-After (CR-A: n=12; placebo immediately before resistance training and creatine immediately after resistance training) or
- Placebo (PLA: n=12; placebo immediately before and immediately after resistance training)
"Participants followed the same supervised whole-body resistance training program for 32 weeks in the same private laboratory. Training sessions were supervised as previous research has demonstrated greater gains compared to unsupervised training (Mazzetti et al. 2000). Prior to training sessions, but after the supplement was consumed, each participant performed a 5-minute stationary cycling warm-up at a self- selected intensity. Participants completed 3 sets of 10 repetitions to muscle fatigue with 1-2 minutes rest between sets for each exercise at an intensity corresponding to their 10- repetition maximum for each exercise.
If you haven't already done so, review the results of J. Antonio's previous creatine timing study in "Creatine Before or After the Workout? Finally the Answer is Here! Study Says: Better Take it After for Mass & Strength" | read more
[...The machine-based program included the following exercises] leg press, chest press, lat pull-down, shoulder press, leg extension, leg curl, triceps extension, biceps curl, calf press, back extension and abdominal curl [all were performed in the given order]" (Candow. 2015).The participants had to maintain daily training logs where the load, number of sets and repetitions
were recorded. Resistance was increased by 2-10 kg once a participant could complete 3 sets of 10 repetitions to muscle fatigue for an exercise. Once the resistance was increased, participants maintained this load until a subsequent 3 sets of 10 repetitions to fatigue were completed.
Don't overestimate the power of timing: These days it appears as if every quack had his own *whatever* timing regimen of which he claims that it was an innovation that would revolutionize your nutrition regimen. If you look at the actual evidence on protein, nutrient and supplement timing, the "advantage" that may exist are yet hilariously small compared to what most people are missing due to not sticking to their diet and training regimen, forgetting about the importance of rest or not striving to increase the weights progressively. So, unless you've optimized all other areas of your diet and training regimen, it would be foolish to even suspect that "timing" may be what's holding you back.
A comparison of the results of the physical examination before and after the 32-week study shows that there was an increase over time for lean tissue mass and muscle strength and a decrease in fat mass (p<0.05) in all groups.
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| Figure 2: The inter-group difference between the strength gains is less pronounced than the one between the mass gains in the creatine before (CR-B) and creatine after (CR-A) groups in this study. |
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| This is by far not the only study which indicates that "Creatine is a potent anti-wheelchair supplement" for your grandpas and grandmas | more |
What I still want to know, though, is taking creatine before and after a workout could not be even more (non-significantly ;-) better | Comment on Facebook!
- Antonio J, Ciccone V. The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strength. J Int Soc Sports Nutr. 2013 Aug 6;10(1):36. [Epub ahead of print]
- Candow, Darren, et al. "Strategic ingestion of creatine supplementation and resistance training in healthy older adults." Applied Physiology, Nutrition, and Metabolism ja.
Post-Workout Coffee Boosts Glycogen Repletion by Up to 30% and May Even Have Sign. Glucose Partitioning Effects
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| Yes, I do suggest that it may be beneficial to drink these two and another two cups of coffee w/ lots of sugar after your workout - if you are an athlete, at least. |
If you look at the existing literature, the effects of post-workout caffeine ingestion are not exactly an intensely researched area. And still, the evidence does more or less strongly support the notion that a post-workout coffee could be as beneficial as its pre-workout analog - in a different area.
You can learn more about coffee at the waredownloadsoft
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| Figure 1: Total glycogen [proglycogen (PG) macroglycogen (MG)] glycogen concentrations during 5 h of recovery in the placebo trial (A) and caffeine trial (B | Battram. 2004). |
"In conclusion, Caf ingestion does not impede the resynthesis of PG or MG after an extensive depletion of muscle glycogen and with the provision of exogenous dietary carbohydrate" (Battram. 2004).As surprising as this may be in view of the inhibitory effect of caffeine on full-body glucose uptake (in Battram's study there was also a significantly higher blood glucose concentration in the caffeine
trial), Battram's results are still no outliers. Rather than that, a follow up study by Pedderson et al. found that, in trained subjects, coingestion of large amounts of Caff (8 mg/kg BM) with CHO has an additive effect on rates of postexercise muscle glycogen accumulation compared with consumption of CHO alone" (Pedderson. 2008).
In that, it is important to point out that the increased glycogen resynthesis in Pedderson's randomized, double-blind crossover study, in which the young well-trained subjects performed intermittent exhaustive cycling and then consumed a low-CHO meal before they rode until volitional fatigue and consumed either
- CHO [4 g/kg body mass (BM)] alone or
- CHO [4 g/kg body mass (BM)] with Caff (8 mg/kg BM)
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| Figure 2: High dose caffeine (8mg/kg) increases glycogen resynthesis after exhausting workouts without having ill effects on the resynthesis of ATP and PCr (Pedderson. 2008). |
Why would you say caffeine may have a partitioning effect? The answer is easy: While fat cells need insulin to transform and store significant amounts of glucose, muscle cells don't - specifically after workouts the increase in GLUT-4 receptor expression and glucose uptake occurs largely without requiring insulin as a trigger. Now, caffeine's ill effects on blood glucose are due to its ability to block the insulin signalling via beta-adrenergic activity (Thong. 2002). It should thus reduce the glucose uptake by the fat cells while decreasing the rate, but not the total amount of glucose that is taken up and stored by the muscle... speaking of rate and total amount: This hypothesis is fully in line with the initially cited study by Battram et al. who observed just that: a decreased rate, but identical total increase in muscle glycogen.
So why haven't we been taking our post-workout caffeine for years, now? Well, I guess the reason is that it is not sure how the effects of caffeine on the sympathetic nervous may effect other factors of the recovery process. In view of the fact the central nervous system will be "on fire" after any workout, though, it is questionable whether adding in 400-800mg caffeine will actually affect its recovery.
A better reason for not (yet) subscribing to the post-workout caffeine binges would thus be that (a) few of us actually need to refill their glycogen stores in 4-6h after a workout and that we (b) have no real clue what the mechanism is. If it was actually - as some of the data would suggest - a selective inhibition of fat cell glucose uptake (see box on the right), even those of us who don't have to restore their glycogen stores as fast as possible may see beneficial effects on body composition. If, on the other hand, it works by stimulating the intestinal absorption of glucose, only (cf. Van Nieuwenhoven. 2000), the real world implications for the average trainee would be significantly less pronounced | Comment on Facebook!
A better reason for not (yet) subscribing to the post-workout caffeine binges would thus be that (a) few of us actually need to refill their glycogen stores in 4-6h after a workout and that we (b) have no real clue what the mechanism is. If it was actually - as some of the data would suggest - a selective inhibition of fat cell glucose uptake (see box on the right), even those of us who don't have to restore their glycogen stores as fast as possible may see beneficial effects on body composition. If, on the other hand, it works by stimulating the intestinal absorption of glucose, only (cf. Van Nieuwenhoven. 2000), the real world implications for the average trainee would be significantly less pronounced | Comment on Facebook!
- Battram, Danielle S., et al. "Caffeine ingestion does not impede the resynthesis of proglycogen and macroglycogen after prolonged exercise and carbohydrate supplementation in humans." Journal of Applied Physiology 96.3 (2004): 943-950.
- Beelen, Milou, et al. "Impact of caffeine and protein on postexercise muscle glycogen synthesis." Med Sci Sports Exerc 44.4 (2012): 692-700.
- Pedersen, David J., et al. "High rates of muscle glycogen resynthesis after exhaustive exercise when carbohydrate is coingested with caffeine." Journal of Applied Physiology 105.1 (2008): 7-13.
- Taylor, Conor, et al. "The effect of adding caffeine to postexercise carbohydrate feeding on subsequent high-intensity interval-running capacity compared with carbohydrate alone." International Journal of Sport Nutrition andExercise Metabolism 21.5 (2011): 410.
- Thong, Farah SL, and Terry E. Graham. "Caffeine-induced impairment of glucose tolerance is abolished by β-adrenergic receptor blockade in humans." Journal of applied physiology 92.6 (2002): 2347-2352.
- Van Nieuwenhoven, M. A., R-JM Brummer, and F. Brouns. "Gastrointestinal function during exercise: comparison of water, sports drink, and sports drink with caffeine." Journal of applied physiology 89.3 (2000): 1079-1085.
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